Designs for Health’s most advanced vitamin K2 formula that targets bone health with clinically studied bone remodeling factors (BRF).* BRF 45™ features 45 mg of vitamin K2 (as MK-4), the research-backed amount shown to promote bone health and strength, arterial health, and help discourage age- and hormone-related bone breakdown in women and men, such as during menopause and andropause.* Vitamins K1 and geranylgeraniol are also included to support conversion to vitamin K2 (as MK-4).*

BRF 45™ may provide nutritional support for individuals who are at risk of bone loss, bone fracture, arterial stiffness, and other relevant conditions in which high amounts of vitamin K1 and/or vitamin K2 may be beneficial.*

††An IPSOS 2023 survey among US functional medicine practitioners, in an average month, Designs for Health is their personally most trusted practitioner supplement brand, meaning a brand that is sold by healthcare practitioners in their office.

††An Ipsos 2023 study among a random sample of 160 functional medicine practitioners including Doctor's of Osteopathic Medicine, Pharmacists, Acupuncturists, Athletic Trainers, Personal Trainers, Fitness Trainer/Coaches, Chiropractors, Integrative Medicine Specialists, Naturopathic Doctor, Homeopaths, Medical Doctors, Physical Therapists, Nurse Practitioner/Physician Assistants, Registered Nurses, Nutritionists, Massage Therapists, Occupational Therapists and Dieticians that are aware of Designs for Health and recommend supplements to their patients.