L-5-MTHF provides 1 mg (1,700 mcg DFE) of natural, biologically active form of folate, which is essential for cell division and growth, and also works to balance the homocysteine pathway.* This formula provides folate in the bioidentical, bioactive form, 5-methyltetrahydrofolate. In L-5-MTHF, the “L” signifies that it is an all-natural [6S] isomer, and this is the active circulating form of folate found in the body and one of the several forms found in food. In nature, this is found only as this [6S] isomer, which is why Designs for Health uses L-5-MTHF, the natural isomer, rather than the mixed (or racemic) form. This product uses the patented folate derivative, Quatrefolic®. This innovative form of folate has demonstrated high bioavailability, solubility, and long-lasting stability. Quatrefolic® L-5-MTHF has been shown to help increase blood folate levels much better than folic acid.*

††An IPSOS 2023 survey among US functional medicine practitioners, in an average month, Designs for Health is their personally most trusted practitioner supplement brand, meaning a brand that is sold by healthcare practitioners in their office.

††An Ipsos 2023 study among a random sample of 160 functional medicine practitioners including Doctor's of Osteopathic Medicine, Pharmacists, Acupuncturists, Athletic Trainers, Personal Trainers, Fitness Trainer/Coaches, Chiropractors, Integrative Medicine Specialists, Naturopathic Doctor, Homeopaths, Medical Doctors, Physical Therapists, Nurse Practitioner/Physician Assistants, Registered Nurses, Nutritionists, Massage Therapists, Occupational Therapists and Dieticians that are aware of Designs for Health and recommend supplements to their patients.