L-5-MTHF provides 5 mg (8,500 mcg DFE) of natural, biologically active folate. Folate is essential for cell division and growth and for proper homocysteine metabolism.* This formula provides folate in the bioidentical, bioactive form, 5-methyltetrahydrofolate (L-5-MTHF). L-5-MTHF (the “L” signifying that it is the all-natural [6S] isomer) is the active circulating form of folate found in the body and one of the several forms found in food. In nature, it is found only as this [6S] isomer, which is why DFH uses L-5-MTHF (as Quatrefolic®), the natural isomer, rather than the mixed (or racemic) form. This innovative form of folate has demonstrated high bioavailability and solubility as well as long-lasting stability. Quatrefolic® L-5-MTHF is superior to folic acid for helping maintain optimal serum folate.*

††An IPSOS 2023 survey among US functional medicine practitioners, in an average month, Designs for Health is their personally most trusted practitioner supplement brand, meaning a brand that is sold by healthcare practitioners in their office.

††An Ipsos 2023 study among a random sample of 160 functional medicine practitioners including Doctor's of Osteopathic Medicine, Pharmacists, Acupuncturists, Athletic Trainers, Personal Trainers, Fitness Trainer/Coaches, Chiropractors, Integrative Medicine Specialists, Naturopathic Doctor, Homeopaths, Medical Doctors, Physical Therapists, Nurse Practitioner/Physician Assistants, Registered Nurses, Nutritionists, Massage Therapists, Occupational Therapists and Dieticians that are aware of Designs for Health and recommend supplements to their patients.