5-MTHF, also known as Methylfolate, is the preferred form of folate supplementation because it is the active form of folate used by the body’s tissues.* 

Many individuals don't get sufficient 5-MTHF (L-5-Methyltetrahydrofolate), the active form of folic acid, because they have intestinal or liver dysfunction, or because they are among the three out of five Americans whose genetic makeup makes it difficult to convert folic acid into active 5-MTHF. 

Benefits of Thorne’s 5-MTHF: 

• An adequate amount of 5-MTHF is essential for the production of the neurotransmitters serotonin, melatonin, dopamine, and epinephrine – all of which support healthy brain function and mood*
• Acting with vitamin B12, 5-MTHF functions as a methyl-group donor, thereby facilitating healthy methylation and homocysteine levels*
• Folic acid is especially important before conception and during early pregnancy, because its biggest need is during the first trimester – when a woman might not know she is pregnant. A folic acid deficiency is linked to low-birth-weight infants and neural tube birth defects*

Note: 1 mg of 5-MTHF is recommended for fetal support during pregnancy; the 15 mg option is recommended only when directed by a health-care practitioner.

Advanced Nutrients is a powerhouse formula that supports health and well-being with added antioxidants from well-studied nutrients and botanicals that contribute to healthy aging.*

Adding a multi-vitamin/mineral supplement to your daily routine is a great first step for promoting good health. However, if you live a lifestyle prone to high levels of oxidative stress due to environmental toxins, chronic stress, smoking, and other factors, you might need a more advanced supplement formula. 

Advanced Nutrients is expertly formulated with essential vitamins, minerals, and additional nutrients from the purest sources and in the most absorbable forms. It provides optimal amounts of key ingredients to create an excellent foundation for good health.* 

This advanced formula offers extra antioxidants that protect your body against cellular damage.

Thorne's Acetyl-L-Carnitine supports the health of the nerves in the upper and lower limbs and enhances the production of the neurotransmitter acetylcholine, which supports brain function.* Acetyl-L-carnitine also helps minimize the discomfort due to alterations in nerve function; for example, in cancer patients undergoing chemotherapy or individual with high blood sugar.* Acetyl-L-carnitine is better absorbed and crosses the blood-brain barrier more rapidly than L-carnitine.* Studies have demonstrated its effectiveness in supporting cognitive health and maintaining a positive mood in the elderly, possibly by partially inhibiting the activity of the hypothalamic-pituitary-adrenal axis and lowering chronically elevated cortisol levels, which become elevated during stress.* In addition to acetyl-L-carnitine's support of brain and nerve health, it also promotes healthy sperm count and motility.*